Inert Dursan Prevents Protein & Biomolecule Sticking & Carryover

April 11 2014 Process Analytical

Duran coated needles

Dursan® offers one solution for diagnostic equipment challenges.    

  • Non-Stick, low friction, inert
  • Protein resistant
  • Ultimate Stability
  • Exceptional Purity
Recent studies by major pharmaceutical and instrument companies have proven Dursan® to be effective in preventing protein and biomolecule sticking and carryover in sampling and delivery systems. 

Dursan demonstrated significant reduction in protein carryover and provided significant benefits to pharma and instrument companies:

  • Reduced protein and biomolecule carryover related false positives
  • Extended the life of injection needles
  • Reduced replacement costs
  • Reduced needle-septa friction, improved automation efficiency
  • Improved corrosion related contamination

Inert Dursan offers benefits in many application areas:

  • LC columns and hardware
  • Laboratory sample preparation and transfer glassware
  • Medical diagnostic testing equipment
  • Delivery needles and transfer components
  • Toxicological/clinical/forensic testing equipment

Dursan® is a very low surface energy, inert coating designed to reduce nonspecific protein binding and carryover while improving corrosion resistance. Medical device manufacturers and diagnostic equipment used for protein analysis will benefit from the durability and unmatched chemical inertness of Dursan coated steel and glass.

Existing techniques for preventing protein sticking such as polyethylene glycol (PEG) systems lack stability and will oxidize in the presence of oxygen, rendering them useless. SilcoTek® provides an alternative coating solution in Dursan® that offers better stability in air and other oxidative environments, even under elevated temperatures.

Learn more about how Dursan can improve the performance of your analytical system.