Dursan® bio-inert coating prevents protein carryover and false readings while improving instrument durability.
Medical device manufacturers, diagnostic equipment and LC instrumentation used for protein analysis benefit from the durability and unmatched chemical inertness of Dursan® coated stainless steel and glass.
For bio-compatibility, confidence, and consistency, use Dursan® on new or existing components.
The protein-resistant properties of Dursan were studied using quartz crystal microbalance with dissipation monitoring (QCM-D), and compared to that of bare stainless steel and a Teflon-like fluoropolymer coating (AF1600).
With the assistance of a nonionic surfactant-containing wash solution, Dursan® was found to facilitate 100% removal of adsorbed proteins (BSA, mouse IgG and NHP), whereas these proteins remain adsorbed on the bare stainless steel surface under same conditions.
Dursan® improves bio-analytical and LC system corrosion resistance
Stainless steel is commonly used throughout LC systems, including needles, columns, pump components, and tubing. Bio-analytical samples interact with metal surfaces and leached metal ions; contaminating the sample and causing inaccurate results.
The common solution to this problem has historically been use of PEEK or other inert non-metallic materials. PEEK, glass and other inert materials have several drawbacks:
- Not durable
- Not able to withstand high pressure
- High cost
- Many LC specific components difficult to make or have limited availability.
- Not able to line small ID tubes
- Poor adhesion to stainless steel surfaces
Dursan® corrosion resistant coating prevents sampling component damage and contamination throughout the analytical flow path. Dursan can coat the ID of the smallest needles, improving durability and preventing protein binding to stainless steel surfaces.
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| Typical coating after bleach exposure |
Dursan after bleach exposure |
Use Dursan® on a wide range of biotechnology equipment:
- HPLC columns and hardware
- Medical diagnostic equipment
- Biomedical devices
- Needles
Give Dursan a try; get a free test coupon and see how Dursan bio-inert coating can improve recovery, and system durability.
